Some malignancies are exceedingly challenging to treat. These cancers include mesothelioma and pseudomyxoma peritonei, also known as peritoneal carcinomatosis, as well as primary colorectal, ovarian, gastric, appendiceal, and cancers that have migrated to the lining surfaces of the peritoneal (abdominal) cavity. Despite significant recent advancements in chemotherapy, the likelihood that treatment will be curative generally is still low, and the patient finds it challenging to deal with the adverse effects. Hyperthermic intraperitoneal chemotherapy (HIPEC), on the other hand, becomes an option for suitable individuals when these malignancies are limited to the peritoneal cavity
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